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LGALS3 (Gene)

Ensembl Gene ID: ENSG00000131981

Entrez Gene ID: 3958

Description: galectin 3

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LGALS3's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LGALS3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LGALS3.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LGALS3.

Gene Sets (4172)

LINCS L1000 Chem Pert Consensus Sigs (1119)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (800)

A gene set library provided by LINCS

rummageo gene perturbations (209)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1704)

A gene set library provided by LINCS

rummageo chemical perturbations (329)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

Human BioMolecular Atlas Program

HuBMAP ASCT-B (2)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	CPCCOEt Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.007414795
	2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.0041673766
	PSB-06126 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.0072309575
	Carvedilol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.0043399627
	3,9-Dihydroxy-benzo[4,5]furo[3,2-c]chromen-6-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.01016438
	thiazolidinecarboxylic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	-0.0141938515
	ST-4034902 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	-0.010766692
	(Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-yl-cyclopentyl]-hept-4-enoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	-0.008913711
	SA-1922975 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.012712963
	4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxylic acid amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	-0.018410785

CPCCOEt
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.007414795

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.0041673766

PSB-06126
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.0072309575

Carvedilol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.0043399627

3,9-Dihydroxy-benzo[4,5]furo[3,2-c]chromen-6-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.01016438

thiazolidinecarboxylic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
-0.0141938515

ST-4034902
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
-0.010766692

(Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-yl-cyclopentyl]-hept-4-enoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
-0.008913711

SA-1922975
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.012712963

4-p-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxylic acid amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
-0.018410785

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.