Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

PPT1 (Gene)

Ensembl Gene ID: ENSG00000131238

Entrez Gene ID: 5538

Description: palmitoyl-protein thioesterase 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PPT1's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PPT1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PPT1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PPT1.

Gene Sets (1024)

LINCS L1000 Chem Pert Consensus Sigs (174)

A gene set library provided by LINCS

GlyGen

GlyGen Glycosylated Proteins 2022 (31)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (158)

A gene set library provided by LINCS

rummageo gene perturbations (185)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (202)

A gene set library provided by LINCS

rummageo chemical perturbations (269)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	PPT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	coenzyme A Metabolite (Entity type)
	PPT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	palmitic acid Metabolite (Entity type)
	KFGENEBIN:PPT1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PPT1 Gene (Entity type)
	3-Hydroxy-1-methoxy-9,10-dioxo-4a,9,9a,10-tetrahydro-anthracene-2-carbaldehyde Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPT1 Gene (Entity type)	0.011650729
	7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PPT1 Gene (Entity type)	-0.00877694
	PPT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Palmitoyl Coenzyme A Metabolite (Entity type)
	PPT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate Metabolite (Entity type)

PPT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
coenzyme A
Metabolite (Entity type)

PPT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
palmitic acid
Metabolite (Entity type)

KFGENEBIN:PPT1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
PPT1
Gene (Entity type)

3-Hydroxy-1-methoxy-9,10-dioxo-4a,9,9a,10-tetrahydro-anthracene-2-carbaldehyde
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPT1
Gene (Entity type)
0.011650729

7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PPT1
Gene (Entity type)
-0.00877694

PPT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Palmitoyl Coenzyme A
Metabolite (Entity type)

PPT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate
Metabolite (Entity type)

DISPLAY PER PAGE

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.