Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

TNFSF10 (Gene)

Ensembl Gene ID: ENSG00000121858

Entrez Gene ID: 8743

Description: TNF superfamily member 10

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TNFSF10's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TNFSF10.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TNFSF10.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TNFSF10.

Gene Sets (7131)

LINCS L1000 Chem Pert Consensus Sigs (1942)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (2077)

A gene set library provided by LINCS

rummageo gene perturbations (158)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (2638)

A gene set library provided by LINCS

rummageo chemical perturbations (304)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Genotype Tissue Expression

GTEx Tissues V8 2023 (4)

A gene set library provided by GTEx

Human BioMolecular Atlas Program

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	tazarotene Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	0.004801647
	Cephalotaxine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.011611953
	[[(1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl]-phenyl-phosphoryl]benzene Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.004536299
	Altrenogest Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.0050007794
	4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.009379397
	KM-03949SC Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.015507529
	(2R,6aS,12aS)-2-Isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydro-6aH-chromeno[3,4-b]furo[2,3-h]chromen-6-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.008389949
	Ethotoin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	0.0047091497
	Securinine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.0078304075
	SID11111534 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.008366922

tazarotene
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
0.004801647

Cephalotaxine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.011611953

[[(1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl]-phenyl-phosphoryl]benzene
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.004536299

Altrenogest
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.0050007794

4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.009379397

KM-03949SC
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.015507529

(2R,6aS,12aS)-2-Isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydro-6aH-chromeno[3,4-b]furo[2,3-h]chromen-6-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.008389949

Ethotoin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
0.0047091497

Securinine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.0078304075

SID11111534
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.008366922

DISPLAY PER PAGE

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.