KDM3A (Gene)

Entrez Gene ID: 55818

Description: lysine demethylase 3A

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View KDM3A's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with KDM3A.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using KDM3A.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for KDM3A.

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Gene Sets (2449)

LINCS L1000 Chem Pert Consensus Sigs (827)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (16)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (255)

A gene set library provided by LINCS

rummageo gene perturbations (193)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (905)

A gene set library provided by LINCS

rummageo chemical perturbations (248)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
isofloxythepin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	-0.0046316376
estramustine-phosphate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	-0.005502911
SID11112716 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	-0.0032511246
theobromine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	-0.0047526658
4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	0.007939581
2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-1-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	0.013243792
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	0.01058093
Amoxapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	0.0041159457
5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	0.028359918
KIN001-242 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	-0.004058907

isofloxythepin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
-0.0046316376

estramustine-phosphate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
-0.005502911

SID11112716
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
-0.0032511246

theobromine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
-0.0047526658

4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
0.007939581

2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-1-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
0.013243792

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
0.01058093

Amoxapine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
0.0041159457

5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
0.028359918

KIN001-242
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
-0.004058907

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.