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CFDE Workbench

FANCL (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:55120, FA complementation group L, FAAP43, FANCL, HGNC:20748, MIM:608111, NM_001114636, NM_001374615, NM_018062, NP_001108108, NP_001361544, NP_060532, NR_156742, NR_164659, PHF9, POG, XM_005264395, XM_011532939, XM_011532940, XM_011532941, XM_011532942, XM_011532944, XM_011532945, XM_017004415, XM_017004416, XP_005264452, XP_011531241, XP_011531242, XP_011531243, XP_011531244, XP_011531246, XP_011531247, XP_016859904, XP_016859905, XR_001738803, XR_002959309, XR_939692
Omim:OMIM:608111
Id:ENSG00000115392
Hgnc:HGNC:20748
Entrez:55120
Ensembl:ENSG00000115392
Description:FA complementation group L
This gene encodes a ubiquitin ligase that is a member of the Fanconi anemia complementation group (FANC). Members of this group are related by their assembly into a common nuclear protein complex rather than by sequence similarity. This gene encodes the protein for complementation group L that mediates monoubiquitination of FANCD2 as well as FANCI. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2018]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FANCL's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with FANCL.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FANCL.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FANCL.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FANCL.

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    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
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