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AMOTL2 (Gene)

Ensembl Gene ID: ENSG00000114019

Entrez Gene ID: 51421

Description: angiomotin like 2

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AMOTL2's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AMOTL2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AMOTL2.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AMOTL2.

Gene Sets (2880)

LINCS L1000 Chem Pert Consensus Sigs (665)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (919)

A gene set library provided by LINCS

rummageo gene perturbations (240)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (706)

A gene set library provided by LINCS

rummageo chemical perturbations (344)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	fentiazac Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	-0.0046643484
	Blebbistatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	-0.008268609
	N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	-0.0073591038
	L-161982 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	0.008971239
	BML-278 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	0.015498512
	8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	-0.003856267
	US9339486, CP55,940 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	-0.00789032
	acivicin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	0.005116983
	1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	0.004817213
	emodic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	0.008739979

fentiazac
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
-0.0046643484

Blebbistatin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
-0.008268609

N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
-0.0073591038

L-161982
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
0.008971239

BML-278
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
0.015498512

8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
-0.003856267

US9339486, CP55,940
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
-0.00789032

acivicin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
0.005116983

1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
0.004817213

emodic-acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMOTL2
Gene (Entity type)
0.008739979

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.