ITK (Gene)

Organism:

Homo sapiens

Synonyms:EMT, ENTREZ:3702, HGNC:6171, IL2 inducible T cell kinase, ITK, LPFS1, LYK, MIM:186973, NM_005546, NP_005537, PSCTK2, XM_017009443, XP_016864932

Omim:OMIM:186973

Nci:C24526

Id:ENSG00000113263

Hgnc:HGNC:6171

Entrez:3702

Ensembl:ENSG00000113263

Description:IL2 inducible T cell kinase

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ITK's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ITK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ITK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ITK.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITK.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	T61-Colon Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE182680 GSE182683 dexamethasone 10 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 10 V 3 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE137325 copanlisib Hair-M 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 etoposide leukocyte 4 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE199107 tryptophan 3 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE135350 XPO1 inhibition Dexamethasone 3 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE135350 dexamethasone 3 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE110178 1 V 7 TRANYLCYPROMINE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

T61-Colon Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE182680 GSE182683 dexamethasone 10 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 10 V 3 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE137325 copanlisib Hair-M 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 etoposide leukocyte 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE199107 tryptophan 3 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE135350 XPO1 inhibition Dexamethasone 3 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE135350 dexamethasone 3 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE110178 1 V 7 TRANYLCYPROMINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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