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PERP (Gene)

Ensembl Gene ID: ENSG00000112378

Entrez Gene ID: 64065

Description: p53 apoptosis effector related to PMP22

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PERP's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PERP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PERP.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PERP.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PERP.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	RAN-03 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.009986889
	JAS07-009 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.013406759
	GW3965 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.011031696
	2-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (quinapril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.0031503423
	SID87457340 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.011646441
	K-145 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.007762994
	Clotrimazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.0062427106
	3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.008688741
	PF750 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.0057443352
	[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.009874801

RAN-03
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
-0.009986889

JAS07-009
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
0.013406759

GW3965
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
0.011031696

2-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (quinapril)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
0.0031503423

SID87457340
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
0.011646441

K-145
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
0.007762994

Clotrimazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
-0.0062427106

3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
0.008688741

PF750
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
-0.0057443352

[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
-0.009874801

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