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CFDE Workbench

HOXB6 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:3216, HGNC:5117, HOX2, HOX2B, HOXB6, HU-2, Hox-2.2, MIM:142961, NM_001369397, NM_018952, NM_156036, NM_156037, NP_001356326, NP_061825, XM_011524727, XP_011523029, homeobox B6
Omim:OMIM:142961
Id:ENSG00000108511
Hgnc:HGNC:5117
Entrez:3216
Ensembl:ENSG00000108511
Description:homeobox B6
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HOXB6's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HOXB6.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HOXB6.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HOXB6.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HOXB6.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE118548 trametinib T84 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE218097 SOX10 overexpression glial cell 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE164874 prednisolone muscle organ 5 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE118548 1 V 2 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE214306 CCM1 knockout 4 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 13 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 8 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE74251 decitabine MCF-7 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE158834 ADIPOR2 knockout HEK293 0 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE118548 trametinib T84 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE218097 SOX10 overexpression glial cell 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164874 prednisolone muscle organ 5 v 9 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE118548 1 V 2 TRAMETINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE214306 CCM1 knockout 4 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 13 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 8 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE74251 decitabine MCF-7 2 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE158834 ADIPOR2 knockout HEK293 0 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
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    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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