SFRP4 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:6424, FRP-4, FRPHE, FRZB-2, HGNC:10778, MIM:606570, NM_003014, NP_003005, PYL, SFRP4, sFRP-4, secreted frizzled related protein 4

Omim:OMIM:606570

Id:ENSG00000106483

Hgnc:HGNC:10778

Entrez:6424

Ensembl:ENSG00000106483

Description:secreted frizzled related protein 4

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SFRP4's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SFRP4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SFRP4.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SFRP4.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SFRP4.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE119978 GSE180930 cisplatin 3 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE235587 mitoxantrone KYSE-70 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE117805 A-66 0 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE102505 tunicamycin 6 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE119978,GSE180930 3 V 4 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE218097 SOX10 overexpression glial cell 2 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233679 nicotinamide 6 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE146358 dopamine 5 v 6 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE156761 dopamine neuron 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE119978 GSE180930 cisplatin 3 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE235587 mitoxantrone KYSE-70 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE117805 A-66 0 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE102505 tunicamycin 6 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE119978,GSE180930 3 V 4 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE218097 SOX10 overexpression glial cell 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233679 nicotinamide 6 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE146358 dopamine 5 v 6 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE156761 dopamine neuron 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.