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GRB10 (Gene)

Ensembl Gene ID: ENSG00000106070

Entrez Gene ID: 2887

Description: growth factor receptor bound protein 10

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GRB10's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GRB10.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GRB10.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GRB10.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GRB10.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	CFTRinh-172 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRB10 Gene (Entity type)	-0.006547345
	Pralidoxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GRB10 Gene (Entity type)	0.0048368117
	topotecan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRB10 Gene (Entity type)	-0.01422121
	KFGENEBIN:GRB10-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	GRB10 Gene (Entity type)
	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GRB10 Gene (Entity type)	0.004880378
	Tetracycline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GRB10 Gene (Entity type)	0.011652687

CFTRinh-172
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRB10
Gene (Entity type)
-0.006547345

Pralidoxime
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GRB10
Gene (Entity type)
0.0048368117

topotecan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRB10
Gene (Entity type)
-0.01422121

KFGENEBIN:GRB10-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
GRB10
Gene (Entity type)

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GRB10
Gene (Entity type)
0.004880378

Tetracycline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GRB10
Gene (Entity type)
0.011652687

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