PLAT (Gene)

Entrez Gene ID: 5327

Description: plasminogen activator, tissue type

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PLAT's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLAT.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PLAT.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PLAT.

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Gene Sets (6256)

LINCS L1000 Chem Pert Consensus Sigs (1786)

A gene set library provided by LINCS

GlyGen Glycosylated Proteins 2022 (44)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1320)

A gene set library provided by LINCS

rummageo gene perturbations (226)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (2509)

A gene set library provided by LINCS

rummageo chemical perturbations (359)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

IDG Drug Targets 2022 (3)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Nicorandil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.011386824
Merbromin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.024364553
(E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	-0.009362468
prostratin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.019412355
[<sup>11</sup>C]doxepin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.0026233355
SID11113504 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	-0.04052783
Tegafur Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	-0.008386033
2-Furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	-0.006164991
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.0065108966
Flumequine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	-0.019469168

Nicorandil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.011386824

Merbromin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.024364553

(E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
-0.009362468

prostratin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.019412355

[<sup>11</sup>C]doxepin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.0026233355

SID11113504
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
-0.04052783

Tegafur
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
-0.008386033

2-Furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
-0.006164991

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.0065108966

Flumequine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
-0.019469168

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.