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PRPS2 (Gene)

Ensembl Gene ID: ENSG00000101911

Entrez Gene ID: 5634

Description: phosphoribosyl pyrophosphate synthetase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRPS2's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRPS2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRPS2.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRPS2.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Daidzein Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRPS2 Gene (Entity type)	0.00837393
	Cefalotin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRPS2 Gene (Entity type)	-0.01921792
	PRPS2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	adenosine monophosphate Metabolite (Entity type)
	SA-1458026 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRPS2 Gene (Entity type)	0.011176582
	SID11113665 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRPS2 Gene (Entity type)	0.007857001
	SA-424589 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRPS2 Gene (Entity type)	0.008074859
	PRPS2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ribose-5-phosphate Metabolite (Entity type)
	PRPS2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Phosphoribosyl Pyrophosphate Metabolite (Entity type)
	PRPS2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)
	alda-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRPS2 Gene (Entity type)	0.0046443646

Daidzein
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRPS2
Gene (Entity type)
0.00837393

Cefalotin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRPS2
Gene (Entity type)
-0.01921792

PRPS2
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
adenosine monophosphate
Metabolite (Entity type)

SA-1458026
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRPS2
Gene (Entity type)
0.011176582

SID11113665
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRPS2
Gene (Entity type)
0.007857001

SA-424589
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRPS2
Gene (Entity type)
0.008074859

PRPS2
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ribose-5-phosphate
Metabolite (Entity type)

PRPS2
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Phosphoribosyl Pyrophosphate
Metabolite (Entity type)

PRPS2
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
atp binding
Metabolite (Entity type)

alda-1
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRPS2
Gene (Entity type)
0.0046443646

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