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CDKN3 (Gene)

Ensembl Gene ID: ENSG00000100526

Entrez Gene ID: 1033

Description: cyclin dependent kinase inhibitor 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CDKN3's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CDKN3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CDKN3.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CDKN3.

Gene Sets (1813)

LINCS L1000 Chem Pert Consensus Sigs (515)

A gene set library provided by LINCS

Knockout Mouse Phenotyping Program

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (465)

A gene set library provided by LINCS

rummageo gene perturbations (186)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (326)

A gene set library provided by LINCS

rummageo chemical perturbations (315)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	clozapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	0.0042615207
	JNJ-7706621 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.007750196
	(4-benzylpiperazino)acetic acid(3-allyl-2-hydroxybenzylidene)hydrazide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.007764595
	VU-0410183-2 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.015574472
	Quinoclamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.008292431
	3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	0.0034939265
	VU-0418946-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.008868314
	wortmannin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.0056039854
	T0156 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	0.0056819795
	CAM-9-021 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	0.0075815953

clozapine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
0.0042615207

JNJ-7706621
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.007750196

(4-benzylpiperazino)acetic acid(3-allyl-2-hydroxybenzylidene)hydrazide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.007764595

VU-0410183-2
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.015574472

Quinoclamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.008292431

3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
0.0034939265

VU-0418946-1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.008868314

wortmannin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.0056039854

T0156
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
0.0056819795

CAM-9-021
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
0.0075815953

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.