SOX10 (Gene)

Organism:

Homo sapiens

Synonyms:DOM, ENTREZ:6663, HGNC:11190, MIM:602229, NM_006941, NP_008872, PCWH, SOX10, SRY-box transcription factor 10, WS2E, WS4, WS4C

Omim:OMIM:602229

Id:ENSG00000100146

Hgnc:HGNC:11190

Entrez:6663

Ensembl:ENSG00000100146

Description:SRY-box transcription factor 10

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SOX10's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SOX10.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SOX10.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SOX10.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SOX10.

Results found

Linked to

	Label	Description
	Ataxia Phenotype (Entity type)	Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of el...
	Sensorineural hearing impairment Phenotype (Entity type)	A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlea...
	GSE153836 11 V 9 FLUOXETINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE210911 CREM knockdown CHL-1 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE214306 CCM1 knockout 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE162892 ISOX 4 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE144373 GSE218070 MHC inhibition 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214931 temozolomide 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE264723 GSE264730 IDH1 inhibition 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE236454,GSE236456 0 V 1 ANGIOTENSIN II MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS

Ataxia

Phenotype (Entity type)

Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of el...

Sensorineural hearing impairment

Phenotype (Entity type)

A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlea...

GSE153836 11 V 9 FLUOXETINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE210911 CREM knockdown CHL-1 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE214306 CCM1 knockout 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE162892 ISOX 4 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE144373 GSE218070 MHC inhibition 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214931 temozolomide 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE264723 GSE264730 IDH1 inhibition 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE236454,GSE236456 0 V 1 ANGIOTENSIN II MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.