DPYSL2 (Gene)

Organism:

Homo sapiens

Synonyms:CRMP-2, CRMP2, DHPRP2, DPYSL2, DRP-2, DRP2, ENTREZ:1808, HGNC:3014, MIM:602463, N2A3, NM_001197293, NM_001244604, NM_001386, NP_001184222, NP_001231533, NP_001377, ULIP-2, ULIP2, dihydropyrimidinase like 2

Omim:OMIM:602463

Id:ENSG00000092964

Hgnc:HGNC:3014

Entrez:1808

Ensembl:ENSG00000092964

Description:dihydropyrimidinase like 2

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DPYSL2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with DPYSL2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DPYSL2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DPYSL2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DPYSL2.

Results found

Linked to

	Label	Description
	GSE179112 GSE179113 hydroxyl Hutt45 4 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE89154 proscillaridin 1 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE171837 bortezomib 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 etoposide leukocyte 7 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE118548 trametinib T84 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE214505 AKR1B1 knockdown A-549 3 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233647 docetaxel UFERSA-PC3 DU145 4 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE115542 digoxin 5 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE252944 AKT inhibition 7 v 9 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE151412 sorafenib 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE179112 GSE179113 hydroxyl Hutt45 4 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE89154 proscillaridin 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE171837 bortezomib 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 etoposide leukocyte 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE118548 trametinib T84 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE214505 AKR1B1 knockdown A-549 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233647 docetaxel UFERSA-PC3 DU145 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE115542 digoxin 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE252944 AKT inhibition 7 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE151412 sorafenib 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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