CFDE Workbench
InfoDataCloudKnowledgetrainingcoordination
Search
Graph
Enrichment
Cross
Assistant
Data Matrix
Use Cases
Tools & Workflows
Submit
Documentation
CFDE Workbench

SI (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:6476, HGNC:10856, MIM:609845, NM_001041, NP_001032, SI, XM_011513078, XP_011511380, sucrase-isomaltase
Omim:OMIM:609845
Id:ENSG00000090402
Hgnc:HGNC:10856
Entrez:6476
Ensembl:ENSG00000090402
Description:sucrase-isomaltase
This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SI's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SI.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SI.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SI.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SI.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE151412 sorafenib 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE77829 SLIRP knockdown LNCaP 3 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE114013 GSE114014 itraconazole 1 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147876 GSE147877 enzalutamide MR42D 2 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE115542 digoxin 5 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE125014 enzalutamide prostate gland 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE158632 quinoline HT-29 Caco-2 3 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE125014 enzalutamide prostate gland 6 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119424 GSE120214 TBXT brachyury inhibition 1 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE151412 sorafenib 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE77829 SLIRP knockdown LNCaP 3 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE114013 GSE114014 itraconazole 1 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147876 GSE147877 enzalutamide MR42D 2 v 11 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115542 digoxin 5 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125014 enzalutamide prostate gland 1 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE158632 quinoline HT-29 Caco-2 3 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125014 enzalutamide prostate gland 6 v 4 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119424 GSE120214 TBXT brachyury inhibition 1 v 4 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

    • DISPLAY PER PAGE
    CFDE Workbench
    Report a bug
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    @CFDE Workbench 2026
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.