LAG3 (Gene)

Organism:

Homo sapiens

Synonyms:CD223, ENTREZ:3902, HGNC:6476, LAG3, MIM:153337, NM_002286, NP_002277, XM_011520956, XP_011519258, lymphocyte activating 3

Omim:OMIM:153337

Id:ENSG00000089692

Hgnc:HGNC:6476

Entrez:3902

Ensembl:ENSG00000089692

Description:lymphocyte activating 3

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LAG3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LAG3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LAG3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LAG3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LAG3.

Results found

Linked to

	Label	Description
	GSE191005 ENL knockout MOLM-13 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE128730 neratinib OVCAR-8 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE129698 SYK inhibition 6 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 3 V 10 FLUDARABINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE199660 1 V 0 SECRETIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE140768 BMI1 inhibition 0 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE152441,GSE152442 0 V 2 FOLIC ACID HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE184784 FACT SUPT16H inhibition Activated natural killer cell therapy 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE115542 digoxin 5 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 11 V 6 FLUDARABINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE191005 ENL knockout MOLM-13 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE128730 neratinib OVCAR-8 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE129698 SYK inhibition 6 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE135030 3 V 10 FLUDARABINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE199660 1 V 0 SECRETIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE140768 BMI1 inhibition 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE152441,GSE152442 0 V 2 FOLIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE184784 FACT SUPT16H inhibition Activated natural killer cell therapy 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE115542 digoxin 5 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE135030 11 V 6 FLUDARABINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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