LY75 (Gene)

Entrez Gene ID: 4065

Description: lymphocyte antigen 75

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LY75's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LY75.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LY75.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LY75.

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Gene Sets (2962)

LINCS L1000 Chem Pert Consensus Sigs (908)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (10)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (762)

A gene set library provided by LINCS

rummageo gene perturbations (91)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1043)

A gene set library provided by LINCS

rummageo chemical perturbations (134)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (8)

A gene set library provided by GTEx

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-419083 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.0061097667
KFGENEBIN:LY75-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)
Amperozide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.008823358
2-(4,4-Difluoropiperidin-1-yl)-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.023336671
Balsalazide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	0.0047905985
exemestane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.0055619795
Acrivastine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.0052489527
mepireserpate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.012450982
(6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.0048642117
SID4253269 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LY75 Gene (Entity type)	-0.0053673806

SA-419083
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.0061097667

KFGENEBIN:LY75-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)

Amperozide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.008823358

2-(4,4-Difluoropiperidin-1-yl)-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.023336671

Balsalazide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
0.0047905985

exemestane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.0055619795

Acrivastine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.0052489527

mepireserpate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.012450982

(6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.0048642117

SID4253269
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LY75
Gene (Entity type)
-0.0053673806

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.