CFH (Gene)

Entrez Gene ID: 3075

Description: complement factor H

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CFH's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CFH.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CFH.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CFH.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CFH.

Gene Sets (4495)

LINCS L1000 Chem Pert Consensus Sigs (998)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (49)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (916)

A gene set library provided by LINCS

rummageo gene perturbations (130)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (772)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1329)

A gene set library provided by LINCS

rummageo chemical perturbations (277)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (9)

A gene set library provided by GTEx

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Levallorphan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	-0.021272331
BMS-833923 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	-0.010438117
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	-0.004603801
SID11112923 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	-0.0106242765
dibenzoylmethane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	0.011341579
5'-guanidinonaltrindole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	0.01026394
iso-olomoucine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	0.008467222
Bivalirudin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	0.0053075505
SID11110714 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	0.011676418
Thioperamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	0.0065797116

Levallorphan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
-0.021272331

BMS-833923
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
-0.010438117

isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
-0.004603801

SID11112923
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
-0.0106242765

dibenzoylmethane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
0.011341579

5'-guanidinonaltrindole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
0.01026394

iso-olomoucine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
0.008467222

Bivalirudin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
0.0053075505

SID11110714
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
0.011676418

Thioperamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
0.0065797116

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Knowledge Graph Assertions

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CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.