MAP3K5 (Gene)

Description: mitogen-activated protein kinase kinase kinase 5

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MAP3K5's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MAP3K5.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MAP3K5.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MAP3K5.

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Gene Sets (1385)

LINCS L1000 Chem Pert Consensus Sigs (622)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (748)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-1459963 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	-0.008174617
SA-101841 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.018748585
PHCCC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.004285557
tripelennamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	-0.007085573
rufloxacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.00798812
SID11112923 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.009830345
hydrastinine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.008154378
SID11113783 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.0072513265
Doxercalciferol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.010115121
Parecoxib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP3K5 Gene (Entity type)	0.015244299