EDEM1 (Gene)

Description: ER degradation enhancing alpha-mannosidase like protein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EDEM1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EDEM1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EDEM1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EDEM1.

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Gene Sets (518)

LINCS L1000 Chem Pert Consensus Sigs (418)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (87)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
bergenin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.009181241
Megestrol Acetate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	0.007216331
N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-indacen-8-yl)-ethyl]-propionamide(S)-(-)-22b Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.0047033248
(2R,3S)-3-(isopropylamino)-1-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)butan-2-ol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	0.01094813
zaldaride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.0044849785
alda-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.0051901555
Tonabersat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.0041494993
5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.0022470264
NPK76-II-72-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.0044414573
TMI-15 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDEM1 Gene (Entity type)	-0.00837652