KMO (Gene)

Description: kynurenine 3-monooxygenase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View KMO's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with KMO.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using KMO.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for KMO.

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Gene Sets (997)

LINCS L1000 Chem Pert Consensus Sigs (556)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (427)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (6)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Kanamycin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	-0.025018765
4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	-0.0036388654
5'-guanidinonaltrindole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	0.012186764
Bisphenol A Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	-0.006646149
BMY 45778 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	-0.010126036
KU-C104233 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	-0.011140257
KMO Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Hydroxykynurenine Metabolite (Entity type)
KMO Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Kynurenine Metabolite (Entity type)
Carbidopa Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	0.0072569964
PATI-1-2-3 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KMO Gene (Entity type)	0.00988886