CFTR (Gene)

Description: CF transmembrane conductance regulator

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CFTR's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CFTR.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CFTR.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CFTR.

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Gene Sets (504)

LINCS L1000 Chem Pert Consensus Sigs (273)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (202)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (15)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
KU-C104142 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	0.011800706
KFGENEBIN:CFTR-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)
1-phenylbiguanide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	-0.014351629
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	-0.008713304
TUL-XX023 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	0.009160801
MW-STK33-100 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	0.013877009

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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CFTR (Gene)

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Gene Sets (504)

Knowledge Graph Assertions

Knowledge Graph Assertions

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Data & Metadata

Tools & Use Cases

Data & Metadata

Tools & Use Cases

Gene Sets (504)

Knowledge Graph Assertions