MAT2A (Gene)

Description: methionine adenosyltransferase 2A

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MAT2A's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MAT2A.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MAT2A.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MAT2A.

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Gene Sets (515)

LINCS L1000 Chem Pert Consensus Sigs (257)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (246)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11113329 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	0.003859149
bruceantin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	-0.018357115
SID11111534 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	-0.0067749047
MAT2A Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
MAT2A Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	methionine Metabolite (Entity type)
Azauridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	-0.010299772
MAT2A Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	S-adenosylmethionine Metabolite (Entity type)
AG-99 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	0.009113546
AT-7519 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	-0.0052451254
Emetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAT2A Gene (Entity type)	-0.011394325