EGLN3 (Gene)

Description: egl-9 family hypoxia inducible factor 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EGLN3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EGLN3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EGLN3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EGLN3.

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Gene Sets (996)

LINCS L1000 Chem Pert Consensus Sigs (503)

A gene set library provided by LINCS

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (481)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	-0.0044085104
Farnesylthiosalicylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	0.0037375358
Tipiracil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	0.004225421
darusentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	0.004770847
oxolinic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	-0.021392737
4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl)-N-quinolin-8-yl-benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	0.0043658586
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	-0.0048701223
2-((1R,2S)-2-(4-(benzyloxy)phenyl)cyclopropylamino)-1-(4-methylpiperazin-1-yl)ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	-0.016232513
2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)	-0.0100522
KFGENEBIN:EGLN3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	EGLN3 Gene (Entity type)