PRKCA (Gene)

Description: protein kinase C alpha

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRKCA's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRKCA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRKCA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRKCA.

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Gene Sets (2136)

LINCS L1000 Chem Pert Consensus Sigs (952)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (1176)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

IDG Drug Targets 2022 (6)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
L-NAME Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.0043362016
L-tryptophan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.007122733
SID103905255 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.003680305
lofexidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.004045383
CCT036477 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	-0.018151438
Siramesine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.0051711155
SA-101776 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.014846241
flunisolide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	-0.006341045
Doxapram Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.0029745507
proxyfan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCA Gene (Entity type)	0.007615582