SMAD3 (Gene)

Description: SMAD family member 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SMAD3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SMAD3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SMAD3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SMAD3.

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Gene Sets (1073)

LINCS L1000 Chem Pert Consensus Sigs (505)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (560)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
GSK2334470 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.005623173
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.010022253
tubocurarine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	-0.006769438
OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.01034224
tamibarotene Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.005960272
SID11113689 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.005219719
SID11114114 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	-0.015791431
4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.009476447
Budesonide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	-0.0069986456
Ro 40-6055 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.008105414