AKR1A1 (Gene)

Description: aldo-keto reductase family 1 member A1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AKR1A1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AKR1A1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AKR1A1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AKR1A1.

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Gene Sets (255)

LINCS L1000 Chem Pert Consensus Sigs (160)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (89)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (3)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Ethanol Metabolite (Entity type)
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	gulonic acid Metabolite (Entity type)
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	glycerol Metabolite (Entity type)
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	glucuronic acid Metabolite (Entity type)
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	acetaldehyde Metabolite (Entity type)
Penicillic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1A1 Gene (Entity type)	-0.011389885
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	NADP Metabolite (Entity type)
KFGENEBIN:AKR1A1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	AKR1A1 Gene (Entity type)
Picrotoxin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1A1 Gene (Entity type)	-0.0059317714
AKR1A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ethanol Metabolite (Entity type)