HMGB3 (Gene)

Description: high mobility group box 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HMGB3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HMGB3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HMGB3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HMGB3.

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Gene Sets (1594)

LINCS L1000 Chem Pert Consensus Sigs (568)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1023)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-432998 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	-0.0091729695
SEW-05685 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	0.010874291
EMF-sumo1-6 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	0.009825771
NSI-189 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	0.0032098894
alendronate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	-0.012550106
BL-050 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	0.006882109
roxithromycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	0.0038551542
N-(4-tert-butylbenzyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	-0.01827729
3-(2-cyano-3-(trifluoromethyl)phenoxy)phenyl 4,4,4-trifluorobutane-1-sulfonate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	-0.008282979
VU-0410183-2 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGB3 Gene (Entity type)	-0.014269241