IQGAP1 (Gene)

Description: IQ motif containing GTPase activating protein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IQGAP1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IQGAP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IQGAP1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IQGAP1.

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Gene Sets (148)

LINCS L1000 Chem Pert Consensus Sigs (98)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (7)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (33)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
L-theanine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	-0.004858047
Pridinol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	0.04582559
2-(2-methoxy-N-methyl-1-(trifluoromethyl)naphthalene-5-carbothioamido)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	-0.0055042906
2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	0.0048732017
methoxamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	0.014633104
dabigatran-etexilate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	0.0031614809
3-Bicyclo[2.2.1]hept-5-en-2-yl-7-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda6-benzo[1,2,4]thiadiazine-6-sulfonic acid amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	-0.04011649
KFGENEBIN:IQGAP1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)
deferoxamine-mesylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IQGAP1 Gene (Entity type)	0.04286578