LAP3 (Gene)

Description: leucine aminopeptidase 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LAP3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LAP3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LAP3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LAP3.

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Gene Sets (1186)

LINCS L1000 Chem Pert Consensus Sigs (778)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (402)

A gene set library provided by LINCS

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Tirofiban Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	0.003571148
Adamantan-1-ylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	-0.0030562999
oseltamivir-carboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	0.004098246
(E)-2-(4-(4-fluorophenoxy)benzylidene)hydrazinecarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	-0.0066224304
SID11113344 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	0.0029982538
SA-425500 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	-0.008542109
cariprazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	0.0048975376
US9138393, Climbazole::US9144538, Climbazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	-0.0043526613
(E)-(3R,5S)-7-[4-(4-Fluoro-phenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid anion Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	-0.003957072
PSB-069 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAP3 Gene (Entity type)	0.009699942