EIF2S3 (Gene)

Description: eukaryotic translation initiation factor 2 subunit gamma

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EIF2S3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EIF2S3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EIF2S3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EIF2S3.

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Gene Sets (2368)

LINCS L1000 Chem Pert Consensus Sigs (1166)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1194)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
amodiaquine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.004917464
(R)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	-0.016475495
Tasquinimod Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.0043007615
PF-04691502 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.009486403
dyphylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.010376275
9-((E)-4-{(2S,3R,4R,5S)-3,4-Dihydroxy-5-[(2S,3S)-3-((1S,2S)-2-hydroxy-1-methyl-propyl)-oxiranylmethyl]-tetrahydro-pyran-2-yl}-3-methyl-but-2-enoyloxy)-nonanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.010708982
zaldaride Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.0048964936
2-Furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	-0.005619668
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	-0.019067908
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.005155428