bursa of Fabricius (Anatomy)

Id:UBERON:0003903

Description:An epithelial and lymphoid organ that develops as a dorsal diverticulum of the proctodeal region of the cloaca in birds. The luminal (interior) surface of the bursa is plicated with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds of bursal follicles containing follicle-associated epithelial cells, lymphocytes, macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics of mature, immunocompetent B cells. The bursa is an organ found in birds involved in B cell differentiation.

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	Label	Description
	5f600a51-8aad-4c85-8417-e96c46838434 Biosample (Entity type)	A biosample from 4DN produced as part of the b0b9c607 f8b4 4f02 93f4 9895b461334b project
	1e459b11-444a-48bc-bc47-f325fb23618c Biosample (Entity type)	A biosample from 4DN produced as part of the b0b9c607 f8b4 4f02 93f4 9895b461334b project
	3ccf2d3c-3c60-463b-a961-39e48f470411 Biosample (Entity type)	A biosample from 4DN produced as part of the 12a92962 8265 4fc0 b2f8 cf14f05db58b project
	a278f0da-8531-443a-aebc-b641c95d7179 Biosample (Entity type)	A biosample from 4DN produced as part of the b0b9c607 f8b4 4f02 93f4 9895b461334b project
	223fb83e-99b5-4504-af28-77d4f013a546 Biosample (Entity type)	A biosample from 4DN produced as part of the 12a92962 8265 4fc0 b2f8 cf14f05db58b project
	44f11267-849a-4621-8fc8-60136819e196 Biosample (Entity type)	A biosample from 4DN produced as part of the 12a92962 8265 4fc0 b2f8 cf14f05db58b project
	1a038ba8-aa43-4361-bd44-283ea1740cda Biosample (Entity type)	A biosample from 4DN produced as part of the 12a92962 8265 4fc0 b2f8 cf14f05db58b project
	425eac62-f5d4-40c1-aaac-33cb61a6931d Biosample (Entity type)	A biosample from 4DN produced as part of the 12a92962 8265 4fc0 b2f8 cf14f05db58b project
	9d7a86b1-9321-4e7c-8112-441a417ded93 Biosample (Entity type)	A biosample from 4DN produced as part of the 12a92962 8265 4fc0 b2f8 cf14f05db58b project
	ff79c53f-9cef-4633-b9a3-b705d93699c4 Biosample (Entity type)	A biosample from 4DN produced as part of the b0b9c607 f8b4 4f02 93f4 9895b461334b project

5f600a51-8aad-4c85-8417-e96c46838434

Biosample (Entity type)

A biosample from 4DN produced as part of the b0b9c607 f8b4 4f02 93f4 9895b461334b project

1e459b11-444a-48bc-bc47-f325fb23618c

Biosample (Entity type)

A biosample from 4DN produced as part of the b0b9c607 f8b4 4f02 93f4 9895b461334b project

3ccf2d3c-3c60-463b-a961-39e48f470411

Biosample (Entity type)