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Toll-like receptor 2 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Toll-like receptor 2 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-3-[(2S)-2,3-di(hexadecanoyloxy)propyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-3-[(2R)-2,4-di(hexadecanoyloxy)butyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	Ethyl 2-(4-methylpiperazine-1-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	2-((R)-2-amino-3-((S)-3-hydroxy-1-methoxy-1-oxopropan-2-ylamino)-3-oxopropylthio)ethyl palmitate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-3-[(2S)-2,3-di(hexadecanoyloxy)propyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-3-methylbutanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	N-((6-Aminopyridin-3-yl)methyl)-9-fluoro-7-hydroxy-3-methyl-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	Phosphoric acid (S)-2-(3-hydroxy-hexadecylcarbamoyl)-2-icosanoylamino-ethyl ester 2-[(2S,3S)-2-(2-1H-indol-3-yl-acetylamino)-3-methyl-pentanoylamino]-ethyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	IC50
	Dodecanoic acid (R)-1-{2-[(S)-3-({2-[2-carboxy-3-(4-hydroxy-phenyl)-propionylamino]-ethoxy}-hydroxy-phosphoryloxy)-2-tetradecanoylamino-propionyloxy]-ethyl}-octyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	IC50
	(2S,5R,9R)-5,27-diamino-2-(hydroxymethyl)-4,12-dioxo-9-(palmitoyloxy)-11,18,21,24-tetraoxa-7-thia-3,14-diazaheptacosan-1-oic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	EC50
	(22R,28R,32R)-1-amino-22-(hydroxymethyl)-28-(23-mercapto-5,21-dioxo-3,10,13,16-tetraoxa-6,20-diazatricosanamido)-1,5,21,24,27-pentaoxo-3,10,13,16-tetraoxa-30-thia-6,20,23,26-tetraazatritriacontane-32,33-diyl dipalmitate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Toll-like receptor 2 Protein (Entity type)	Ki

(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-3-[(2S)-2,3-di(hexadecanoyloxy)propyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-3-[(2R)-2,4-di(hexadecanoyloxy)butyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

Ethyl 2-(4-methylpiperazine-1-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

2-((R)-2-amino-3-((S)-3-hydroxy-1-methoxy-1-oxopropan-2-ylamino)-3-oxopropylthio)ethyl palmitate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-3-[(2S)-2,3-di(hexadecanoyloxy)propyl]sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-6-aminohexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-3-methylbutanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

N-((6-Aminopyridin-3-yl)methyl)-9-fluoro-7-hydroxy-3-methyl-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

Phosphoric acid (S)-2-(3-hydroxy-hexadecylcarbamoyl)-2-icosanoylamino-ethyl ester 2-[(2S,3S)-2-(2-1H-indol-3-yl-acetylamino)-3-methyl-pentanoylamino]-ethyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
IC50

Dodecanoic acid (R)-1-{2-[(S)-3-({2-[2-carboxy-3-(4-hydroxy-phenyl)-propionylamino]-ethoxy}-hydroxy-phosphoryloxy)-2-tetradecanoylamino-propionyloxy]-ethyl}-octyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
IC50

(2S,5R,9R)-5,27-diamino-2-(hydroxymethyl)-4,12-dioxo-9-(palmitoyloxy)-11,18,21,24-tetraoxa-7-thia-3,14-diazaheptacosan-1-oic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
EC50

(22R,28R,32R)-1-amino-22-(hydroxymethyl)-28-(23-mercapto-5,21-dioxo-3,10,13,16-tetraoxa-6,20-diazatricosanamido)-1,5,21,24,27-pentaoxo-3,10,13,16-tetraoxa-30-thia-6,20,23,26-tetraazatritriacontane-32,33-diyl dipalmitate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Toll-like receptor 2
Protein (Entity type)
Ki

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