Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

Splicing factor 3B subunit 3 (Protein)

Description: A protein in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Splicing factor 3B subunit 3 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

Report a bug

Data & Metadata

Tools & Use Cases

@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Data & Metadata

Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-(N-[G-3H]-ethylcarbamoyloxy)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	(R,2E,4E)-6-(4-(dimethylamino)benzoyl)-N-hydroxy-4-methylhepta-2,4-dienamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	pladienolide E Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	pladienolide A Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	Tacrolimus Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-7-{N-[(5S)-6-{N-methyl-N-[2-(N-methyl-N-{5-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]amino}-6-oxo-5-(N-{4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzoyl}amino)hexyl]carbamoyloxy}-18,19-epoxytricosa-8,12,14-triene-11-olide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-(N-{2-[2-(2-{N-[5-(5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uido-3-yl)pentanoyl]amino}ethoxy)ethoxy]ethyl}carbamoyloxy)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	pladienolide C Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	(3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50
	pladienolides D Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Splicing factor 3B subunit 3 Protein (Entity type)	IC50

(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-(N-[G-3H]-ethylcarbamoyloxy)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

(R,2E,4E)-6-(4-(dimethylamino)benzoyl)-N-hydroxy-4-methylhepta-2,4-dienamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

pladienolide E
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

pladienolide A
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

Tacrolimus
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-7-{N-[(5S)-6-{N-methyl-N-[2-(N-methyl-N-{5-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]amino}-6-oxo-5-(N-{4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzoyl}amino)hexyl]carbamoyloxy}-18,19-epoxytricosa-8,12,14-triene-11-olide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-(N-{2-[2-(2-{N-[5-(5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uido-3-yl)pentanoyl]amino}ethoxy)ethoxy]ethyl}carbamoyloxy)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

pladienolide C
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

(3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

pladienolides D
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Splicing factor 3B subunit 3
Protein (Entity type)
IC50

DISPLAY PER PAGE