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Peptidyl-prolyl cis-trans isomerase D (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Peptidyl-prolyl cis-trans isomerase D 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(R)-1-((5-ethyl-4-oxo-1,2,3,4,5,6-hexahydrobenzo[b][1,5]diazocin-8-yl)methyl)-3-(2-(2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	IC50
	2-(exo-3,5-Dioxo-4-aza-tricyclo[5.2.1.0(2,6)]dec-4-yl)-N-((1R,9R,10S)-10-hydroxy-12-oxa-8-aza-tricyclo[7.3.1.0(2,7)]trideca-2(7),3,5-trien-4-ylmethyl)-acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	IC50
	2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-N-(4-sulfamoylphenyl)thiazole-5-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	Kd
	1-(((2R,3S,6R)-3-hydroxy-2,3,4,6-tetrahydro-1H-2,6-methanobenzo[c][1,5]oxazocin-8-yl)methyl)-3-(2-((R)-2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	IC50
	5-(4-((4R,5R,E)-5-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-5-hydroxy-4-methylpent-1-enyl)benzylcarbamoyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	Ki
	rac-2-(3,5-Dioxo-4-aza-tricyclo[5.2.1.0(2,6)]dec-4-yl)-N-(1,2,3,4-tetrahydro-quinolin-6-ylmethyl)-acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	IC50
	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:Q08752-1 CUI Isoform (Entity type)
	(R)-1-(4-Aminobenzyl)-3-(2-(2-(2-bromophenyl)pyrrolidin-1-yl)-2-oxoethyl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	Ki
	(R)-1-(4-aminobenzyl)-3-(2-(2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	Kd
	1-(4-Aminobenzyl)-3-((S)-4-(methylthio)-1-((S)-2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-1-oxobutan-2-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Peptidyl-prolyl cis-trans isomerase D Protein (Entity type)	Ki

(R)-1-((5-ethyl-4-oxo-1,2,3,4,5,6-hexahydrobenzo[b][1,5]diazocin-8-yl)methyl)-3-(2-(2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
IC50

2-(exo-3,5-Dioxo-4-aza-tricyclo[5.2.1.0(2,6)]dec-4-yl)-N-((1R,9R,10S)-10-hydroxy-12-oxa-8-aza-tricyclo[7.3.1.0(2,7)]trideca-2(7),3,5-trien-4-ylmethyl)-acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
IC50

2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-N-(4-sulfamoylphenyl)thiazole-5-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
Kd

1-(((2R,3S,6R)-3-hydroxy-2,3,4,6-tetrahydro-1H-2,6-methanobenzo[c][1,5]oxazocin-8-yl)methyl)-3-(2-((R)-2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
IC50

5-(4-((4R,5R,E)-5-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-5-hydroxy-4-methylpent-1-enyl)benzylcarbamoyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
Ki

rac-2-(3,5-Dioxo-4-aza-tricyclo[5.2.1.0(2,6)]dec-4-yl)-N-(1,2,3,4-tetrahydro-quinolin-6-ylmethyl)-acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
IC50

Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:Q08752-1 CUI
Isoform (Entity type)

(R)-1-(4-Aminobenzyl)-3-(2-(2-(2-bromophenyl)pyrrolidin-1-yl)-2-oxoethyl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
Ki

(R)-1-(4-aminobenzyl)-3-(2-(2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
Kd

1-(4-Aminobenzyl)-3-((S)-4-(methylthio)-1-((S)-2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-1-oxobutan-2-yl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Peptidyl-prolyl cis-trans isomerase D
Protein (Entity type)
Ki

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