Broad substrate specificity ATP-binding cassette transporter ABCG2 (Protein)

Description: A protein in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Broad substrate specificity ATP-binding cassette transporter ABCG2 's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Dimethyl 3,3'-(((2,2'-((((((4,4'-(((Pyridin-4-ylmethyl)azanediyl)bis(methylene))bis(1H-1,2,3-triazole-4,1-diyl))-bis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(4,1-phenylene))bis(4-oxo-4H-chromene-3,2-diyl))bis(oxy))bis(methylene))dibenzoate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	EC50
N-(3-Methoxyphenyl)-6-nitro-2-(pyridin-3-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	IC50
N-(2-(2-phenyl-2H-tetrazol-5-yl)phenyl)-1-naphthamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	IC50
6-Methyl-N,2-diphenylpyrimidin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	IC50
N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-2-carbonyl)-amino]-terephthalamic acid methyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	IC50
2-Nitro-4-((2-(pyridin-3-yl)quinazolin-4-yl)amino)phenol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	EC50
5-[2-(4-Methoxyphenyl)ethyl]-5,6,7,8-tetrahydroindeno[1,2-b]-indole-9,10-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	IC50
2-[4-[2-[2-[2-[4-[[benzyl-[[1-[2-[2-[2-[4-(3-benzyloxy-4-oxo-chromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-3-benzyloxy-chromen-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	EC50
(2R,3R)-5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)chroman-3-yl 3-(3,4-dimethoxybenzamido)-4-fluorobenzoate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	IC50
3-(Benzyloxy)-2-(4-(2-(2-(2-(4-(3-(4-(7-fluoro-4-oxo-4H-chromen-2-yl)phenoxy)propyl)-1H-1,2,3-triazol-1-yl)-ethoxy)ethoxy)ethoxy)phenyl)-4H-chromen-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	EC50

Dimethyl 3,3'-(((2,2'-((((((4,4'-(((Pyridin-4-ylmethyl)azanediyl)bis(methylene))bis(1H-1,2,3-triazole-4,1-diyl))-bis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(4,1-phenylene))bis(4-oxo-4H-chromene-3,2-diyl))bis(oxy))bis(methylene))dibenzoate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
EC50

N-(3-Methoxyphenyl)-6-nitro-2-(pyridin-3-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
IC50

N-(2-(2-phenyl-2H-tetrazol-5-yl)phenyl)-1-naphthamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
IC50

6-Methyl-N,2-diphenylpyrimidin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
IC50

N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-2-carbonyl)-amino]-terephthalamic acid methyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
IC50

2-Nitro-4-((2-(pyridin-3-yl)quinazolin-4-yl)amino)phenol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
EC50

5-[2-(4-Methoxyphenyl)ethyl]-5,6,7,8-tetrahydroindeno[1,2-b]-indole-9,10-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
IC50

2-[4-[2-[2-[2-[4-[[benzyl-[[1-[2-[2-[2-[4-(3-benzyloxy-4-oxo-chromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-3-benzyloxy-chromen-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
EC50

(2R,3R)-5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)chroman-3-yl 3-(3,4-dimethoxybenzamido)-4-fluorobenzoate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
IC50

3-(Benzyloxy)-2-(4-(2-(2-(2-(4-(3-(4-(7-fluoro-4-oxo-4H-chromen-2-yl)phenoxy)propyl)-1H-1,2,3-triazol-1-yl)-ethoxy)ethoxy)ethoxy)phenyl)-4H-chromen-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
EC50

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.