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Dual specificity protein kinase CLK1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Dual specificity protein kinase CLK1 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SID124360148 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	AC50
	SID124360156 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	AC50
	(S)-8-(Benzo[d][1,3]dioxol-5-yl)-1-(1-(4-fluorophenyl)-ethyl)-1H-[1,2,3]triazolo[4,5-c]quinolone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	IC50
	N6-(3-amino-5-chlorophenyl)-N2-((1S,2R)-2-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	IC50
	4-(3-isopropyl-2-methyl-imidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	IC50
	1-(4-Fluorobenzyl)-8-(2-methylpyridin-4-yl)-1H-[1,2,3]-triazolo[4,5-c]quinolone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	IC50
	(Z)-3-(pyridin-3-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)acrylonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	IC50
	Dual specificity protein kinase CLK1 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:P49759-1 CUI Isoform (Entity type)
	milciclib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	Kd
	SID4237899 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity protein kinase CLK1 Protein (Entity type)	AC50

SID124360148
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
AC50

SID124360156
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
AC50

(S)-8-(Benzo[d][1,3]dioxol-5-yl)-1-(1-(4-fluorophenyl)-ethyl)-1H-[1,2,3]triazolo[4,5-c]quinolone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
IC50

N6-(3-amino-5-chlorophenyl)-N2-((1S,2R)-2-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
IC50

4-(3-isopropyl-2-methyl-imidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
IC50

1-(4-Fluorobenzyl)-8-(2-methylpyridin-4-yl)-1H-[1,2,3]-triazolo[4,5-c]quinolone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
IC50

(Z)-3-(pyridin-3-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)acrylonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
IC50

Dual specificity protein kinase CLK1
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:P49759-1 CUI
Isoform (Entity type)

milciclib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
Kd

SID4237899
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity protein kinase CLK1
Protein (Entity type)
AC50

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