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Melanocyte-stimulating hormone receptor (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Melanocyte-stimulating hormone receptor 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(2S)-2-acetamido-N-[(1R)-2-[[(1R)-2-[[(1S)-2-[[(1R)-2-[[(1S)-1-[[(1S)-2-[[(1R)-2-amino-2-oxo-1-(sulfanylmethyl)ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]amino]-1-benzyl-2-oxo-ethyl]amino]-1-(1H-imidazol-5-ylmethyl)-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]-5-guanidino-pentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	EC50
	(S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	EC50
	US9447148, 9.24 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	Ki
	Cyclopropanecarboxylic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-2-(3H-imidazol-4-yl)-ethyl]-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	EC50
	H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	EC50
	(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((R)-2-acetamidohexanamido)-6-(3-guanidinopropyl)-1,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	EC50
	US8846601, 153::US9458201, 153 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	Ki
	(11S,14S,17S,20R,23S)-23-((1H-imidazol-4-yl)methyl)-14-((1H-indol-3-yl)methyl)-17-(3-guanidinopropyl)-20-(naphthalen-2-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexaazaspiro[5.19]pentacosane-11-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	IC50
	(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((R)-2-acetamidohexanamido)-6-(3-guanidinopropyl)-1,4,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	Kd
	(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-thiophen-2-yl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Melanocyte-stimulating hormone receptor Protein (Entity type)	EC50

(2S)-2-acetamido-N-[(1R)-2-[[(1R)-2-[[(1S)-2-[[(1R)-2-[[(1S)-1-[[(1S)-2-[[(1R)-2-amino-2-oxo-1-(sulfanylmethyl)ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]amino]-1-benzyl-2-oxo-ethyl]amino]-1-(1H-imidazol-5-ylmethyl)-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]-5-guanidino-pentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
EC50

(S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
EC50

US9447148, 9.24
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
Ki

Cyclopropanecarboxylic acid [(S)-1-((S)-1-{(S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-2-(3H-imidazol-4-yl)-ethyl]-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
EC50

H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
EC50

(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((R)-2-acetamidohexanamido)-6-(3-guanidinopropyl)-1,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
EC50

US8846601, 153::US9458201, 153
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
Ki

(11S,14S,17S,20R,23S)-23-((1H-imidazol-4-yl)methyl)-14-((1H-indol-3-yl)methyl)-17-(3-guanidinopropyl)-20-(naphthalen-2-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexaazaspiro[5.19]pentacosane-11-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
IC50

(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((R)-2-acetamidohexanamido)-6-(3-guanidinopropyl)-1,4,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
Kd

(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-thiophen-2-yl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Melanocyte-stimulating hormone receptor
Protein (Entity type)
EC50

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