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Endoplasmic reticulum aminopeptidase 1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Endoplasmic reticulum aminopeptidase 1 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50
	((1R)-1-Amino-3-phenylpropyl)[(2'S)-2'-((2'S)-2'-carbamoylpyrrolidine-1'-carbonyl)-4'-methylpentyl]phosphinic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50
	((1R)-1-Amino-3-phenylpropyl){(2'S)-2'-[((2'S)-1'-amino-1'-oxo-3'-phenylpropan-2'-yl)carbamoyl]-4'-methylpentyl}-phosphinic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50
	(S)-Benzyl 2-(4-Amino-3-((S)-2-aminohexanamido)-benzamido)-3-(1H-indol-3-yl)propanoate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50
	3-((1-amino-3-(4-(hydroxymethyl)phenyl)propyl)phosphino)-2-benzylpropanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	Ki
	((1R)-1-Amino-3-phenylpropyl){(2'S)-3'-[((2'S)-1'-amino-1'-oxo-3'-phenylpropan-2'-yl)amino]-2'-{[3-(4-methoxyphenyl)-isoxazol-5-yl]methyl}-3'-oxopropyl}phosphinic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50
	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:Q9NZ08-1 CUI Isoform (Entity type)
	(4aR,5S,6R,8S,8aR)-5-(2-(Furan-3-yl)ethyl)-8-hydroxy-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid ammonium salt Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50
	SID125001269 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	AC50
	((1R)-1-Amino-3-phenylpropyl){(2'S)-2'-[((2'S)-1'-amino-4'-methyl-1'-oxopentan-2'-yl)carbamoyl]-4'-methylpentyl}-phosphinic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endoplasmic reticulum aminopeptidase 1 Protein (Entity type)	IC50

4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

((1R)-1-Amino-3-phenylpropyl)[(2'S)-2'-((2'S)-2'-carbamoylpyrrolidine-1'-carbonyl)-4'-methylpentyl]phosphinic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

((1R)-1-Amino-3-phenylpropyl){(2'S)-2'-[((2'S)-1'-amino-1'-oxo-3'-phenylpropan-2'-yl)carbamoyl]-4'-methylpentyl}-phosphinic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

(S)-Benzyl 2-(4-Amino-3-((S)-2-aminohexanamido)-benzamido)-3-(1H-indol-3-yl)propanoate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

3-((1-amino-3-(4-(hydroxymethyl)phenyl)propyl)phosphino)-2-benzylpropanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
Ki

((1R)-1-Amino-3-phenylpropyl){(2'S)-3'-[((2'S)-1'-amino-1'-oxo-3'-phenylpropan-2'-yl)amino]-2'-{[3-(4-methoxyphenyl)-isoxazol-5-yl]methyl}-3'-oxopropyl}phosphinic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:Q9NZ08-1 CUI
Isoform (Entity type)

(4aR,5S,6R,8S,8aR)-5-(2-(Furan-3-yl)ethyl)-8-hydroxy-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid ammonium salt
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

SID125001269
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
AC50

((1R)-1-Amino-3-phenylpropyl){(2'S)-2'-[((2'S)-1'-amino-4'-methyl-1'-oxopentan-2'-yl)carbamoyl]-4'-methylpentyl}-phosphinic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endoplasmic reticulum aminopeptidase 1
Protein (Entity type)
IC50

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