3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-oxo-5-alpha-steroid 4-dehydrogenase 1 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(4aR,6aS)-7-(3,4-Dihydro-2H-quinoline-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-N-(1,1,1-trifluoro-2-phenylpropan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
8-Bromo-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
(10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid tert-butylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
(4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1,4a,6a-trimethyl-10-phenyl-hexadecahydro-indeno[5,4-f]quinolin-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
4-methyl-1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
N-Benzyl-N-((4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-formamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2,6-dimethyl-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50
(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-methoxy-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 1 Protein (Entity type)	IC50

(4aR,6aS)-7-(3,4-Dihydro-2H-quinoline-1-carbonyl)-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-indeno[5,4-f]quinolin-2-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-N-(1,1,1-trifluoro-2-phenylpropan-2-yl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

8-Bromo-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

(10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid tert-butylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

(4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1,4a,6a-trimethyl-10-phenyl-hexadecahydro-indeno[5,4-f]quinolin-2-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

4-methyl-1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

N-Benzyl-N-((4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-formamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (2,6-dimethyl-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-methoxy-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein (Entity type)
IC50

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