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Muscarinic acetylcholine receptor M1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Muscarinic acetylcholine receptor M1's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	arecoline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)
	4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-yl)methylamino)ethyl)cyclohexanol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	Ki
	1-{4-[3-(3-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,2,5]thiadiazol-3-yl}-4-aza-tricyclo[2.2.1.02,6]heptane Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	EC50
	3-(4'-chlorobiphenyl-4-yl)-N-(4-(piperidin-1-ylmethyl)phenyl)propanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	IC50
	(R)-1-(3-phenoxypropyl)-3-(9H-xanthene-9-carboxamido)-1-azoniabicyclo[2.2.2]octane bromide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	IC50
	(3S,3aR,4R,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl-piperidin-2-yl)-ethyl]-3-methyl-decahydro-naphtho[2,3-c]furan-1-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	Ki
	3-(R)-Methyl-N-methyl-2-methylamino-N-((3S,3aS,5aS,5bR,9S,11aR,13aR)-2,3,11a-trimethyl-2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13-hexadecahydro-1H-2-aza-pentaleno[1,6a-a]phenanthren-9-yl)-butyramide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	Ki
	AE9C90CB Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	-
	2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	Ki
	(R)-1-(4-methylpiperazin-1-yl)-2,3-diphenylpropan-1-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M1 Protein (Entity type)	IC50

arecoline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)

4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-yl)methylamino)ethyl)cyclohexanol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
Ki

1-{4-[3-(3-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,2,5]thiadiazol-3-yl}-4-aza-tricyclo[2.2.1.0*2,6*]heptane
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
EC50

3-(4'-chlorobiphenyl-4-yl)-N-(4-(piperidin-1-ylmethyl)phenyl)propanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
IC50

(R)-1-(3-phenoxypropyl)-3-(9H-xanthene-9-carboxamido)-1-azoniabicyclo[2.2.2]octane bromide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
IC50

(3S,3aR,4R,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl-piperidin-2-yl)-ethyl]-3-methyl-decahydro-naphtho[2,3-c]furan-1-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
Ki

3-(R)-Methyl-N-methyl-2-methylamino-N-((3S,3aS,5aS,5bR,9S,11aR,13aR)-2,3,11a-trimethyl-2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13-hexadecahydro-1H-2-aza-pentaleno[1,6a-a]phenanthren-9-yl)-butyramide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
Ki

AE9C90CB
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
-

2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
Ki

(R)-1-(4-methylpiperazin-1-yl)-2,3-diphenylpropan-1-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M1
Protein (Entity type)
IC50

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