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Heat shock protein 75 kDa, mitochondrial (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Heat shock protein 75 kDa, mitochondrial 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	luminespib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	IC50
	Geldanamycin-Cy3b Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	Kd
	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:Q12931-1 CUI Isoform (Entity type)
	5-(2-amino-4-chloro-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methylpent-4-yn-2-ol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	Ki
	(4E,6Z,8R,9S,10E,12S,13R,14S,16R)-19-(2-(dimethylamino)ethylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	Ki
	6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	Ki
	4-Chloro-1-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	IC50
	1-((6-bromobenzo[d][1,3]dioxol-5-yl)methyl)-4-chloro-1H-pyrazolo-[3,4-d]pyrimidin-6-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	IC50
	Geldanamycin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	IC50
	8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein 75 kDa, mitochondrial Protein (Entity type)	IC50

luminespib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
IC50

Geldanamycin-Cy3b
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
Kd

Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:Q12931-1 CUI
Isoform (Entity type)

5-(2-amino-4-chloro-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methylpent-4-yn-2-ol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
Ki

(4E,6Z,8R,9S,10E,12S,13R,14S,16R)-19-(2-(dimethylamino)ethylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
Ki

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
Ki

4-Chloro-1-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
IC50

1-((6-bromobenzo[d][1,3]dioxol-5-yl)methyl)-4-chloro-1H-pyrazolo-[3,4-d]pyrimidin-6-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
IC50

Geldanamycin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
IC50

8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein 75 kDa, mitochondrial
Protein (Entity type)
IC50

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