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Beta-3 adrenergic receptor (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Beta-3 adrenergic receptor 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(R)-N-cyclopentyl-2-(3-(3-(4-(6-(2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)hexyloxy)butyl)phenyl)ureido)acetamide acetate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	ethyl 1-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)benzoyl)piperidine-4-carboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	(4-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenylsulfamoyl}-phenyl)-carbamic acid phenethyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	(S)-2-(2-Aminothiazol-4-yl)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-propanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propylamino)phenyl)oxazole-4-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	N-{4-[2-((R)-2-Hydroxy-2-phenyl-ethylamino)-ethyl]-phenyl}-4-[4-(1H-indol-3-yl)-thiazol-2-ylmethyl]-benzenesulfonamideN-{4-[2-((R)-2-Hydroxy-2-phenyl-ethylamino)-ethyl]-phenyl}-4-(4-pyridin-3-yl-thiazol-2-ylmethyl)-benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	(+/-)-7-(4-(22-(2-allylphenoxy)-21-hydroxy-2,9-dioxo-13,16-dioxa-3,10,19-triazadocosyloxy)styryl)-5,5-difluoro-3-(thiophen-2-yl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	Kd
	Thiophene-2-sulfonic acid ((R)-3-{1-hydroxy-2-[2-(1H-indol-3-yl)-ethylamino]-ethyl}-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	3-Phenyl-propane-1-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	EC50
	N-(5-((S)-3-((R)-2-(2-chlorophenyl)-1-(3,4-dimethoxyphenyl)ethylamino)-2-hydroxypropyl)-2-hydroxyphenyl)methanesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-3 adrenergic receptor Protein (Entity type)	Ki

(R)-N-cyclopentyl-2-(3-(3-(4-(6-(2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)hexyloxy)butyl)phenyl)ureido)acetamide acetate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

ethyl 1-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)benzoyl)piperidine-4-carboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

(4-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenylsulfamoyl}-phenyl)-carbamic acid phenethyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

(S)-2-(2-Aminothiazol-4-yl)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-propanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propylamino)phenyl)oxazole-4-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

N-{4-[2-((R)-2-Hydroxy-2-phenyl-ethylamino)-ethyl]-phenyl}-4-[4-(1H-indol-3-yl)-thiazol-2-ylmethyl]-benzenesulfonamideN-{4-[2-((R)-2-Hydroxy-2-phenyl-ethylamino)-ethyl]-phenyl}-4-(4-pyridin-3-yl-thiazol-2-ylmethyl)-benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

(+/-)-7-(4-(22-(2-allylphenoxy)-21-hydroxy-2,9-dioxo-13,16-dioxa-3,10,19-triazadocosyloxy)styryl)-5,5-difluoro-3-(thiophen-2-yl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
Kd

Thiophene-2-sulfonic acid ((R)-3-{1-hydroxy-2-[2-(1H-indol-3-yl)-ethylamino]-ethyl}-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

3-Phenyl-propane-1-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
EC50

N-(5-((S)-3-((R)-2-(2-chlorophenyl)-1-(3,4-dimethoxyphenyl)ethylamino)-2-hydroxypropyl)-2-hydroxyphenyl)methanesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-3 adrenergic receptor
Protein (Entity type)
Ki

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