4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK1 Protein (Entity type)	IC50
4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK2 Protein (Entity type)	IC50
4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Non-receptor tyrosine-protein kinase TYK2 Protein (Entity type)	IC50
4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK3 Protein (Entity type)	IC50

4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK1
Protein (Entity type)
IC50

4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK2
Protein (Entity type)
IC50

4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Non-receptor tyrosine-protein kinase TYK2
Protein (Entity type)
IC50

4-((1R,3S)-3-amino-2,2,3-trimethylcyclopentylamino)-6-p-tolylpyrrolo[1,2-b]pyridazine-3-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK3
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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