(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent noradrenaline transporter Protein (Entity type)	IC50
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	G-protein coupled receptor family C group 6 member A Protein (Entity type)	IC50
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Beta-2 adrenergic receptor Protein (Entity type)	IC50
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent dopamine transporter Protein (Entity type)	IC50
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 5 Protein (Entity type)	-
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Extracellular calcium-sensing receptor Protein (Entity type)	IC50
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2D6 Protein (Entity type)	IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent noradrenaline transporter
Protein (Entity type)
IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
G-protein coupled receptor family C group 6 member A
Protein (Entity type)
IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Beta-2 adrenergic receptor
Protein (Entity type)
IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent dopamine transporter
Protein (Entity type)
IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 5
Protein (Entity type)
-

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Extracellular calcium-sensing receptor
Protein (Entity type)
IC50

(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2D6
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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