3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINA1 Gene (Entity type)	0.0072019817
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GLRX Gene (Entity type)	-0.0054968502
THZ-2-98-01 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	0.5314938426017761
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SORD Gene (Entity type)	0.005577435
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-(1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione Compound (Entity type)	0.6107431650161743
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LBH Gene (Entity type)	-0.0069957995
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.0061316094
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BTG1 Gene (Entity type)	-0.0057080174
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	-0.0070941555
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM158 Gene (Entity type)	0.0055312687

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINA1
Gene (Entity type)
0.0072019817

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GLRX
Gene (Entity type)
-0.0054968502

THZ-2-98-01
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
0.5314938426017761

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SORD
Gene (Entity type)
0.005577435

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-(1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione
Compound (Entity type)
0.6107431650161743

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LBH
Gene (Entity type)
-0.0069957995

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
0.0061316094

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BTG1
Gene (Entity type)
-0.0057080174

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
-0.0070941555

3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM158
Gene (Entity type)
0.0055312687

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