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JAK3 inhibitor II (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View JAK3 inhibitor II's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	JAK3 inhibitor II Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA1 Gene (Entity type)	-0.009021682
	Manidipine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	JAK3 inhibitor II Compound (Entity type)	0.2655949294567108
	JAK3 inhibitor II Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN1 Gene (Entity type)	-0.009045806
	JAK3 inhibitor II Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Broad substrate specificity ATP-binding cassette transporter ABCG2 Protein (Entity type)	EC50
	JAK3 inhibitor II Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	-0.013452884
	JAK3 inhibitor II Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PD-198306 Compound (Entity type)	0.5510199666023254
	JAK3 inhibitor II Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MME Gene (Entity type)	0.009708859
	JAK3 inhibitor II Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SDC4 Gene (Entity type)	-0.009371947
	JAK3 inhibitor II Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	0.009533635
	JAK3 inhibitor II Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.014528272

JAK3 inhibitor II
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHLDA1
Gene (Entity type)
-0.009021682

Manidipine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
JAK3 inhibitor II
Compound (Entity type)
0.2655949294567108

JAK3 inhibitor II
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN1
Gene (Entity type)
-0.009045806

JAK3 inhibitor II
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein (Entity type)
EC50

JAK3 inhibitor II
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
-0.013452884

JAK3 inhibitor II
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PD-198306
Compound (Entity type)
0.5510199666023254

JAK3 inhibitor II
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MME
Gene (Entity type)
0.009708859

JAK3 inhibitor II
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SDC4
Gene (Entity type)
-0.009371947

JAK3 inhibitor II
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT13
Gene (Entity type)
0.009533635

JAK3 inhibitor II
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
-0.014528272

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