(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fer Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Focal adhesion kinase 1 Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase Chk2 Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	NUAK family SNF1-like kinase 1 Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribosomal protein S6 kinase alpha-3 Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribosomal protein S6 kinase alpha-2 Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	ALK tyrosine kinase receptor Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fes/Fps Protein (Entity type)	IC50
(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribosomal protein S6 kinase alpha-6 Protein (Entity type)	IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Fer
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Focal adhesion kinase 1
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase Chk2
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
NUAK family SNF1-like kinase 1
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribosomal protein S6 kinase alpha-3
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribosomal protein S6 kinase alpha-2
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
ALK tyrosine kinase receptor
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Fes/Fps
Protein (Entity type)
IC50

(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribosomal protein S6 kinase alpha-6
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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